Lopinavir & Ritonavir

Lopimune 50 mg/200 mg Capsule is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection.






 Lopinavir & Ritonavir

Manufactured By



 60 Tablets


 Anti-HIV Drug


Lopimune is a combination drug composed of two antiretroviral medicines namely Lopinavir and Ritonavir. Manufactured by Cipla, it is widely used in antiretroviral therapy to treat HIV patients.



Lopimune tablets are used to treat HIV infections.

It can also be used as a PEP or Post-Exposure Prophylaxis to prevent HIV in suspected cases of exposure.


How do the Lopimune tablets work?

Lopimune consists of a low dose of Ritonavir, 50 mg combined with a larger dose of Lopinavir, about 200 mg. Both of these constituents are protease inhibitors. These stop HIV viruses from producing new viruses and multiplying by blocking their access to protease.

These are not a cure for HIV but when taken in combination with other antiretrovirals, these drugs can decrease HIV viral load on the body and eventually make it undetectable.  


Side Effects

Here are some of the commonly reported side effects of Lopimune,

  • Nausea

  • Vomiting

  • Diarrhea

  • Dizziness

  • Mild redness

  • Itchiness

  • Rashes

  • An increase or decrease in body fat

  • High blood sugar or hyperglycemia

  • Diabetes

  • Kidney stones

  • Stomach pain

  • Increased blood lipid levels

Usually, the side effects go away without any treatment in particular. But if these persist or worsen consult your doctor.

In some cases, there may be severe side effects, like liver damage, gallbladder issues, heart problems.


Risks to consider

Antiretroviral Medications like Lopimune can cause immune reconstitution inflammatory syndrome (or IRIS) as the immune system rebuilds itself. This may often cause some infections to suddenly exacerbate. This is generally taken as a sign of recovery.

People with pre-existing heart conditions must exercise caution before taking these tablets. Let your doctor know about any such conditions.

If you have a history of liver issues or kidney issues, let your doctor know beforehand. On consultation, your doctor may prescribe another tablet with fewer side effects or risks for you.

Overall the risks of not treating HIV outweigh the side effects that these medications may cause. 



Take Lopimune tablets as prescribed by your doctor. Do not chew or crush the tablet, swallow it whole with a glass of water. This medication must be taken with food for optimal results.